Welcome to the Sternberg Lab!
Our laboratory is interested in the systems biology of nematodes. We seek to understand how the properties of an organism are encoded in its genome.
September 2018. We were awared a two-year grant from the NIH-NIMH to generate cGAL drivers for every neuron class and test them by perturbing neurons during male mating behavior.
Quintero-Cadena P, Sternberg PW. Enhancer sharing promotes neighborhoods of transcriptional regulation across eukaryotes. G3 (Bethesda) 2016 Oct. 31. pii g3.116.036228. doi: 10.1534/g3.116.036228. [Epub ahead of print]
Wang H, Liu J, Gharib S, Chai CM, Schwarz E, Pokala N, Sternberg PW. cGAL, a temperature-robust GAL4-UAS system for Caenorhabditis elegans. Nature Methods. 2016 Dec. 19. doi:10.1038/nmeth.4109. [Epub ahead of print]
Hsueh YP, Gronquist MR, Schwarz EM, Nath RD, Lee CH, Gharib S, Schroeder FC, Sternberg PW. Nematophagous fungus Arthrobotrys oligospora mimics olfactory cues of sex and food to lure its nematode prey. eLife. 2017 Jan. 18. doi:10.7554/eLife.20023
Sternberg PW. In Retrospect: Forty years of cellular clues from worms. Nature. 2017 March 29. 543(7647), 628-630
Chai CM, Cronin CJ, Sternberg PW. Automated analysis of a nematode population-based chemosensory preference assay. Jove 2016 April. In press.
Angeles-Albores D, Leighton DHW, Tsou T, Khaw TH, Antoshechkin I, Sternberg PW. The Caenorhabditis elegans female state: Decoupling the transcriptomic effedts of aging and sperm-status. G3. 2017 July 17. https://doi.org/10.1534/g3.117.300080 [Epub ahead of print]